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KMID : 1130320090520010129
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Korean Journal of Pediatrics
2009 Volume.52 No. 1 p.129 ~ p.132
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Changes in N-terminal pro-B-type natriuretic peptide in a neonate with symptomatic isolated left ventricular noncompaction
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Song Ji-Hyeun
Kim Yeo-Hyang
Kim Chun-Soo
Lee Sang-Lak
Kwon Tae-Chan
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Abstract
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We describe here our experience with a neonate presenting with cyanosis, grunting, and cardiomegaly, who was diagnosed with isolated left ventricular noncompaction (IVNC) by echocardiography. The patient had high levels of N-terminal pro-B-type natriuretic peptide (NT pro-BNP) and symptoms of heart failure including poor feeding and tachypnea. During the period in which NT pro-BNP levels steadily increased, the patient suffered sudden cardiac arrest despite heart failure management. Following cardiopulmonary resuscitation, cardiac arrest was resolved, NT pro-BNP levels decreased, and all symptoms showed improvement. We consider that assessment of NT pro-BNP with cardiac functional analysis using echocardiography could help in the prediction of disease progress in IVNC.
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KEYWORD
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Newborn, Myocardium, Natriuretic peptide, Brain
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